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Allergix IgG4 Food Antibodies 90 - Serum

IgG4 Delayed Food Reactions

What is an IgG4 response?

IgG4 antibodies are associated with non-atopic or "delayed" food reactions that can worsen or contribute to many different health problems. These reactions are considered the most common form of immunologically mediated food intolerance.

An IgG4 response to food is actually more common than the IgE response, which causes an immediate reaction. These reactions are more difficult to notice since they can occur hours or even days after consumption of an offending food. In some cases, a person's reaction to a food may occur several days after eating the offending food and the link between the food and their symptoms may not be connected. These "hidden" food allergies are caused by increasing blood levels of IgG4 antibodies in reaction to specific foods.

Metametrix Innovation in IgG Antibody Testing

  • New patent-pending IgG4 assay allows our test to show less false positives leading to better patient compliance.
  • First test to quantitate IgG4
  • Eliminates non-specific binding, lowering false positives without rejecting true positives

Common offending foods eaten frequently and hard to avoid:

  • Milk
  • Corn
  • Wheat
  • Egg
  • Foods processed with molds such as black tea, breads, and fruit juices

Metametrix offers two Allergix IgG4 Food Antibody Profiles:

  • IgG4 Food Antibody Profile - measures serum levels of IgG4 antibodies specific to 90 food antigens. A four-day rotation diet is included.
  • Bloodspot IgG4 Food Antibody Profile - measures levels of IgG4 antibodies specific to 30 common offending foods from an easy-to-use finger stick.  A four-day rotation diet is included.

Special Pricing is available for the following combination profiles:

  • 0270 - IgG4 and IgE Food Antibodies
  • 0278 - IgG4 Food Antibodies and Celiac Profile
Clinicians: Order Now! Patients: Get Started!
"An exclusion diet based on food-specific serum IgG4 antibody testing may provide a useful adjunct in IBS patients, and testing may provide an objective and quick method for selecting an exclusion diet for treating such patients."


-Scand J Gastroenterol. 2005 Jul;40(7):8007

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